Endocrine Abstracts

Case description: A 32-year-old male patient was treated with remdesivir and high-dose steroid for severe COVID-19 pneumonia in an ICU for one month. He was later diagnosed with steroid-induced diabetes mellitus. An endocrinological consultation raised the possibility of endogenous Cushing’s syndrome. He was then referred to our department for further investigation of suspected Cushing’s syndrome (CS). The patient presented with typical physical signs and symptoms of...

Introduction: Medullary thyroid carcinoma (MTC) in multiple endocrine neoplasia type 2B (MEN2B) syndrome is associated with RET mutation. Patients harbouring de novo mutations are usually diagnosed in more advanced stages of the disease. We present the case of a young female patient with MEN2B diagnosed with stage IV medullary thyroid carcinoma at the age of 10 years.Aim: Characterizing the efficacy of the different sequences of therapies and disease pro...

Introduction: Adrenocortical carcinoma (ACC) is a rare tumor known for its diverse biological behaviour and generally poor prognosis. Recently, the S-GRAS scoring system has emerged as an accurate prognostic model, incorporating the most frequently used clinicopathological parameters: ENSAT stage, grade, resection status, age at diagnosis, and tumor symptoms. So far, this system’s efficacy has only been validated in extensive multicenter studies, proposing it as a reliabl...

Introduction: Hypertension is a severe medical condition that significantly increases mortality and disability worldwide. Most hypertensive patients are classified with essential hypertension; however, secondary hypertension is present 5–10% of all cases. Aortic stenosis is a significant cause of secondary hypertension in children and adolescents. Middle-aortic syndrome constitutes 0.5%–2% of all cases of aortic stenosis. The stenosis involves the abdominal aorta a...